A study led by the Digestive Endoscopy Unit, awarded two statewide scholarships

The randomized multicenter study BAMPI trial (NCT 04595058) has been designed to clarify the possible benefits of a technical variant in transmural biliary drainage guided by echoendoscopy in malignant biliary pathology.

The Digestive Endoscopy Unit is leading a state-wide multicenter project with the participation of seven tertiary centers (Mútua de Terrassa, Ramón y Cajal-Madrid, Rio Hortega-Valladolid, Alicante, Clínic Valencia, Castellón and Bellvitge). The aim is to evaluate whether the addition of a coaxial plastic prosthesis to luminal apposition prostheses represents a clinical benefit in transmural drainage due to tumor biliary obstruction.

Obstruction of the bile duct by tumor pathology (e.g., pancreatic or bile duct cancer) is a common clinical scenario in our environment and bile duct drainage poses a technical challenge. Innovations within interventional echoendoscopy have led to a breakthrough in cases where the standard technique through the papilla via ERCP (retrograde endoscopic cholangiopancreatography) fails. Being an innovative technique, the prospective and randomized scientific literature is limited to resolving doubts. For this reason, the BAMPI (Biliary Apposing Metal Pigtail) clinical trial will provide solid scientific evidence on biliary drainage guided by echoendoscopy, as well as whether adding a pigtail decreases the percentages of biliary reobstructions of prostheses and therefore , reduces reinterventions.

Dr. Sumalla Albert Garcia, coordinator of the study, has received two grants competitive major scientific societies: the grant of initial research of digestive Catalan Society (SCD) and a research grant from the Spanish Society of Digestive Endoscopy (SEED). This study is part of his doctoral project, with Dr. Joan Gornals as thesis director and principal investigator of the clinical trial.